This guide contains information about places where you can stop for the night when driving from Fayetteville, North Carolina to Myrtle Beach, South Carolina. Total distance for the trip is around 120 miles with a driving time of approximately 2 hours 3 mins. Cities and towns with hotels that are on the fastest route between Fayetteville and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)